By Luke Sholl


Can you mix cannabis and magic mushrooms? Does this mind-altering pair produce a synergistic effect, or will you just end up having a bad trip? Although the biochemistry behind both a cannabis high and a shroom trip is understood, interactions between these processes remain somewhat of a mystery. Continue reading as we walk you through the difference between the two, and see if weed and shrooms work well together.

Do Cannabis and Psychedelics Mix?

Cannabis and psychedelic fungi are natural sources of chemical compounds—cannabinoids and alkaloids, respectively—that produce altered states of consciousness following consumption. With use spanning far back into human history, various cultures have consumed natural psychoactive substances for a variety of reasons, ranging from the holistic to the ceremonial. Today, they are still used for these purposes in different parts of the world, and many people also use them for recreational purposes or to expand their consciousness.

Because cannabis and psychedelics produce distinct effects on the body and brain, users often mix them in hopes of experiencing a synergistic effect. 

While no clinical trials have outlined the safety or efficacy of taking cannabis and magic mushrooms together, anecdotal reports detail varying effects. Some users report that high-CBD products help to reduce the side effects of shrooms while high-THC levels assist in amplifying the hallucinogenic effects. Below, you’ll discover everything you need to know about mixing cannabis and magic mushrooms.

Growing Cannabis Alongside Mushrooms

But before we get into the effects—what’s the consensus on growing weed and mushrooms together? Should you cultivate the two side by side? For the most part, probably not.

Mushrooms require extra care and attention to stay hydrated and free from contamination. Whereas weed growers can simply toss seeds into the soil, mushroom growers need to sterilise their growing medium to destroy competing microbes. To achieve the first flush, growers use either jars or monotubs to create an environment high in humidity and CO₂ that works to keep contaminating microbes out. In contrast, cannabis requires a lower humidity and higher levels of oxygen to thrive.

However, following the first harvest, growers can transition their fully colonised mushroom substrate, now more resistant to contamination, into their cannabis grow room or garden in hopes of a second flush. Growers often opt to place this mycelium cake around the base of their plants, mulch it with straw and manure, and water it in. If conditions are right, you’ll see a second flush emerge in the not-too-distant future. If nothing happens, nothing goes to waste; the spent growing medium and threads of hyphae in the cake are a source of nitrogen and other nutrients that will feed your soil.

Cannabis vs Magic Mushrooms

To understand the compatibility between these two substances, it helps to break down how they differ. For one, weed and mushrooms belong to entirely different kingdoms of life. Belonging to the kingdom Plantae, cannabis plants are autotrophic organisms that create energy through photosynthesis.

In contrast, psilocybin mushrooms belong to the kingdom Fungi; they’re heterotrophic organisms that release enzymes to externally digest their food before taking up smaller molecules.

Aside from these evolutionary differences, cannabis and mushrooms have drastically different effects on the human brain.

Consumption

The way a person consumes a substance changes the way said substance acts in the body. The route of administration influences the onset, duration, and even what secondary chemicals are created as a result of different metabolic pathways. As one of the most versatile plants, there are myriad ways to consume cannabis. However, options are limited when it comes to magic mushrooms.

  • Cannabis

Many people choose to smoke cannabis because of the simple process and fast onset of effects. However, concerned with the toxic byproducts of smoking, many have now turned to vaporizing their herb.

Cannabis edibles are renowned for their potency. Eating cannabis-infused foods or consuming cannabis-infused beverages exposes cannabinoids to first-pass metabolism. This converts the primary psychoactive molecule THC into the more potent metabolite 11-hydroxy-THC. As such, oral intake of cannabis features a longer onset and duration.

Sublingual administration (placing cannabis extracts under the tongue) sends cannabinoids directly into the bloodstream. This route of administration provides a rapid onset without the need to inhale smoke or vapor.

Cannabis can even be applied to the skin as a cream or lotion, although a negligible amount of THC will reach the bloodstream.

Cannabis vs Magic Mushrooms
  • Shrooms

Shrooms are either eaten fresh or dried on their own, added to other foods, or made into tea. The “lemon tek” method has become particularly popular among psychonauts, and involves soaking magic mushrooms in lemon or lime juice for a faster-acting effect and a better taste. Of course, there are many other ways to eat mushrooms, such as infusing them into chocolate bars or making blue honey.

That said, the oral route remains the most viable way to take this form of fungi. If you’re wondering if you can smoke magic mushrooms, you technically can, but it likely reduces their potency.

Step 1

Effects

Cannabis produces hundreds of different compounds that belong to several chemical families, including cannabinoids, terpenes, and flavonoids. However, the cannabinoid THC underpins the psychoactive effects of the herb.

Likewise, psilocybin mushrooms contain several alkaloids known for their ability to alter consciousness: psilocybin, psilocin, and baeocystin.

  • Cannabis

High-THC cannabis strains and extracts produce a “high” often characterised by feelings of euphoria, creativity, and open-mindedness. Typical side effects include red eyes, dry mouth, increased appetite, and anxiety. Edible cannabis, through the conversion of THC into 11-hydroxy-THC, produces a more potent effect that borders on the psychedelic. As such, negative side effects like paranoia, anxiety, and panic are potentially more likely.

Cannabis vs Magic Mushrooms
  • Shrooms

Psilocybin mushrooms produce a much more intense cognitive experience, depending on the dose. While small doses give rise to euphoria and enhanced senses, high doses are associated with full-blown hallucinations, ego death, and a complete but transient disconnect from reality in some cases.

Step 1

Mechanism of Action

As a “classical psychedelic”, magic mushrooms target different pathways in the brain than THC. With that in mind, the mechanisms of action of each substance give us a closer look into their potential synergy or lack thereof.

  • Cannabis

How does THC get you high? Following inhalation, the molecule enters the bloodstream and slips through the blood–brain barrier. Once inside the brain, THC binds to CB1 receptors, which results in an acute boost of dopamine—a neurotransmitter heavily involved in reward and feelings of well-being. But THC doesn’t work alone. Aromatic terpenes and other cannabinoids, such as CBD, work in concert to steer these effects toward relaxing or energising outcomes, for example. Edible THC, as mentioned above, takes a different route in the body, but ultimately also stimulates CB1 receptors.

  • Shrooms

Alongside LSD, mescaline, and DMT, psilocybin ranks as a classical psychedelic—a compound that interfaces with the serotonergic system. When psilocybin enters the body, metabolic processes swiftly dephosphorylate (convert) the molecule into the metabolite psilocin, which binds to serotonin receptors. Under normal chemical conditions, serotonin (the chief ligand of this system) binds to these receptors to help maintain normal cognitive function. However, by tweaking this system slightly, psilocin manages to catalyse a profound temporary change in cognitive processing.

What Happens When You Combine Cannabis and Magic Mushrooms?

So, what about mixing weed and shrooms? Does it cause a bad trip, or does it give rise to synergistic effects? In truth, we aren’t really sure of exactly how the two work together, and there’s no real science to back up any conjecture. However, anecdotal reports give us insight into the potential compatibility between psilocybin and cannabis. The results of combining the two appears to depend chiefly on the cannabinoids in question and the dose of mushrooms consumed.

THC vs CBD

While most people who mix cannabis and shrooms choose to smoke THC-rich weed to boost the psychoactive nature of the overall experience, others find that taking CBD alongside mushrooms helps to lessen side effects and promote a peaceful experience.

If you’re someone who experiences a lot of pre-trip anxiety, or who experiences anxiety when using THC in isolation, perhaps either opt for cannabidiol or exclude cannabis from your tripping ventures altogether.

How to Use Cannabis and Magic Mushrooms Together

But if you do want to combine them, how should you go about mixing weed and shrooms? Some prefer smoking before a trip, others during, and others when coming back down to Earth. Here are some recommendations for riding the THC and shroom wave at different points of your journey. Note that we do not necessarily recommend taking edible THC while tripping, as there is more potential for side effects and discomfort.

Before a Magic Mushroom Trip

 Blazing up before a mushroom trip helps some users get into the correct mental state before voyaging into a trippier world. For those who are a bit on edge before tripping, high-CBD varieties can help the mind and body relax, while high-THC weed helps some trippers—especially daily stoners—settle comfortably into their surroundings.

How to Use Cannabis and Magic Mushrooms Together

During a Magic Mushroom Trip

Smoking cannabis during a trip requires at least some experience with psychedelics. Opting for high-THC flowers and extracts will likely enhance the mind-altering nature of the experience, particularly at around the two-hour mark, when the mushrooms begin to peak. Lighting up again around the four-hour mark, as the effects begin to fade, will help to prolong the experience.

How to Use Cannabis and Magic Mushrooms Together

After a Magic Mushroom Trip

As the afterglow begins to take hold, many users find that smoking cannabis helps them to gently float back down to Earth, reflect on what they just experienced, and think of ways to integrate what they learned into their life going forward.

How to Use Cannabis and Magic Mushrooms Together

Should You Mix Cannabis With Magic Mushrooms?

It’s totally up to you. Both cannabis and mushrooms have relatively good safety profiles. However, the main risks revolve around mental health issues; both are best avoided by those experiencing, or predisposed to, such conditions.

We also don’t know exactly how chemicals in cannabis and magic mushrooms interact. For example, CBD disrupts the metabolism of a wide range of drugs and slows down the rate at which the body processes them. If you choose to use cannabis and magic mushrooms together, we recommend experiencing them both individually beforehand. Then, proceed by going “low and slow” until you familiarise your mind and body with this botanical and fungal combination.

Promoting Responsible Cannabis UseRQS emphasizes the importance of responsible cannabis consumption.

While many individuals use cannabis frequently without complications, some may be susceptible to developing adverse behaviours. We believe the herb should enhance one’s life, not hinder it.

Responsible use involves limiting consumption to adults only, refusing to operate cars or machinery while under the influence, and making an effort to resist abuse.

Stay Cultivated.

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Privacy Policy - Royal Queen Seeds

To ensure a safe online environment and guarantee adequate data protection, we strictly comply with all legal requirements. In this privacy statement, we provide information about how and for what purpose data is collected, safety measures, storage periods and contact details.


COMPANY NAME: SNORKEL SPAIN, SL (hereinafter ROYAL QUEEN SEEDS)

C/ Vilar d'Abdelà, 5 (nave 1) CP: 08170 de Montornès del Vallès

+34 937 379 846

support@royalqueenseeds.com


The present Privacy Policy sets out the terms on which we will treat personal data at ROYAL QUEEN SEEDS; this includes any personal data collected through our website https://www.royalqueenseeds.com/ as well as any other data we process in the course of our business activities.

ROYAL QUEEN SEEDS collects the following personal data for the purposes listed below:

SECTION 1 – PERSONAL INFORMATION WE COLLECT

1.1 Account purchases

Account purchases can only be made if you are in possession of a personal account. When you create an account or purchase something from our shop, as part of the buying and selling process we collect the following personal information that you provide to us:

This information is required for delivery. In addition, when you browse our shop, we automatically receive the Internet Protocol (IP) address of your computer. Based on this information, we can optimise your online experience and at the same time protect our online environment.

Purpose of data collection

We collect and store account-related data for the following purposes:

(a) to carry out obligations arising from any contracts between you and us, and to provide you with information, products and services that you may request from us;

(b) to set up, manage and communicate with you about your account and your orders;

(c) to conduct market research and analysis;

(d) to confirm your age and identity, and to detect and prevent fraud.

1.2 Newsletters

With your explicit permission, we may send you newsletters about our shop, new products and other updates. We send newsletters based on your explicit consent. In the event that you purchase a product, and in accordance with current regulations, we may send you commercial communications in accordance with the legitimate interest of our company, always about products or services similar to those you have purchased or contracted. In any case, you may exercise your right of opposition through the channels announced in this Privacy Policy. The following information is collected in relation to the newsletter:

We do not need to know the sex of the person in order to send the newsletter (data minimisation: by law we must ask for data that is strictly necessary to provide the service, and in this case knowing the sex is not necessary to send the newsletter).

Purpose of data collection

The data collected is used to:

(a) personalise our emails, including your name and gender;

(b) provide gender-specific content.

You can withdraw your consent at any time by using the link provided in the newsletter or the contact information provided in section 2.

1.3 Customer service and contact form

In order to provide appropriate support, our customer service employees have access to information related to the account. Consequently, their support will be highly effective and friendly. The data provided in our contact form is used by our CRM provider, SuperOffice. We will only use your details to respond to your message.

SECTION 2 – LEGITIMATE INTEREST

If you have purchased any of our products, please note that we may process your personal data for promotional purposes, based on Royal Queen Seeds' legitimate interest only to offer you products or services from our company and about products or services similar to those you have purchased. You may exercise your right to opt out of future messages by the means set out in this Privacy Policy or through any notification you receive.

2.1 How do you withdraw consent?

If you change your mind, you can withdraw your consent for us to contact you for the purpose of collecting, using, or disclosing your data at any time by reaching out to us at: support@royalqueenseeds.com.

SECTION 3 – DISCLOSURE

We may disclose your personal information if we are required to do so by law or if you breach our Terms of Service.

SECTION 4 – HOW LONG DO WE KEEP YOUR DATA?

At Royal Queen Seeds, we will not retain your data for longer than is necessary for the purposes described in this Policy. Different retention periods apply for different types of data; however, the longest period we will normally hold any personal data is 10 years.

4.1 Account information

Data relating to the account remains relevant for as long as the consumer is in possession of an account. Therefore, the data remains documented for as long as the account exists. When our customers delete an account, the associated data will be deleted within a reasonable period of time. Requests regarding the inspection or correction of stored personal data or the deletion of an account can be sent to support@royalqueenseeds.com.

4.2 Newsletters

In the event that you give us your consent to inform you about our products or services, we will keep your data until you express your wish not to receive any further communications from us. However, we regularly (every month) carry out a relevance check. Registered customers (and their personal information) will be deleted whenever customers do not reply to our request. In addition, our newsletter mailing has an opt-out feature. Consumers can withdraw their consent by using this opt-out feature.

SECTION 5 – COOKIES

Cookies are small information files that notify your computer of previous interactions with our website. These cookies are stored on your hard drive, not on our website. Essentially, when you use our website, your computer displays its cookies to us, informing our site that you have visited before. This allows our website to function more quickly and remember aspects related to your previous visits (such as your username), making your experience more convenient. At Royal Queen Seeds, we use two types of cookies: functional and analytical.

5.1 Functional Cookies

Functional cookies are used to enhance your online experience. Among other things, these cookies track what is added to your shopping cart. The use of these cookies does not require prior authorization.

5.2 Analytical Cookies

Analytical cookies are used for research and market analysis. The data collected with these analytical cookies is anonymous, making it unusable for third parties. The use of these cookies does not require prior authorization.

SECTION 5 – THIRD-PARTY SERVICES

Third-party services are required to conduct transactions and provide our services. In general, the third-party providers we use will only collect, use and disclose your information to the extent necessary to enable them to perform the services they provide to us.

However, certain third-party service providers, such as payment gateways and other payment transaction processors, have their own privacy policies regarding the information we must provide to them for your transactions.

We encourage you to read the privacy policies of these providers so that you can understand how these providers will handle your personal information.

In particular, certain suppliers may be located or have facilities located in a different jurisdiction than yours or ours. Therefore, if you choose to proceed with a transaction involving the services of a third party, your information may be subject to the laws of the jurisdiction in which that service provider or its facilities are located.

Once you leave our website or are redirected to a third-party website or application, you are no longer governed by this Privacy Policy or the Terms of Service of our website.

Web analytics service (anonymous data)

On this website we have integrated an element of a web analytics service (with anonymisation functionality). Web analytics can be defined as the gathering, processing and analysis of data about the behaviour of visitors to websites. An analytics service collects, among other things, data about which website a person came from (the so-called referrer), which sub-pages they visited or how often and for how long they visited a sub-page. Web analytics is mainly used for website optimisation and for a cost–benefit analysis of internet advertising.

Courier service

To complete deliveries we use a courier service. This courier service carries out the delivery between our company and the consumer's home. To complete these logistics, the company requires access to the consumer's name and address information.

Mailing service

Royal Queen Seeds uses a third-party mail service provider to send its newsletter. This provider has access to limited account information related to opt-in consent (e.g. email address).

Marketing services

Royal Queen Seeds has the support of a company that specialises in marketing and communication activities. Their access to personal information is very limited and mostly anonymous.

Payment services

At Royal Queen Seeds we use external payment services to handle our transactions (e.g. credit card payments).

SECTION 6 – SECURITY

To protect your personal information, we take reasonable precautions and follow industry standard best practices to ensure that it is not inappropriately lost, misused, accessed, disclosed, altered or destroyed.

If you provide us with your credit card information, the information is encrypted using secure socket layer technology (SSL) and stored using AES-256 encryption. Although no method of transmission over the internet or electronic storage is 100% secure, we follow all PCI-DSS requirements and implement additional industry standards that are commonly accepted. Information related to the account is protected with a hashing method. This method transforms the information into a generated hash. As a result, confidential information is protected and invisible, even to us. In addition, our databases are exceptionally protected against unauthorised access. For example, access to the database is only possible and permitted via approved IP addresses (e.g. from Royal Queen Seeds headquarters). Other attempts and addresses are rejected at all times.

Furthermore, data is anonymised as much as possible, so it cannot be directly linked to a specific consumer. With this data, however, we may be able to carry out market research and analysis. In addition, the third parties concerned (e.g. mailing service) are examined prior to our collaboration, comply with the GDPR from the EU and receive a processing agreement. Within Royal Queen Seeds, employees are assigned different access permissions. Specific permission provides access only to information that is strictly required to perform a task. Digital security measures are subject to change and must meet high requirements to ensure the safety of online customers. That is why, at Royal Queen Seeds, we appoint a security officer. Regular verification and improvement of security measures (where necessary) are part of the role.

SECTION 7 – CHANGES TO THIS PRIVACY POLICY

We reserve the right to modify this Privacy Policy at any time, so please check back regularly. Changes and clarifications will be effective immediately upon being published on the Website. If we make substantial changes to this policy, we will notify you here that it has been updated so you will know what information we collect, how we use it and under what circumstances, if any, we use and/or disclose it.

SECTION 8 – YOU HAVE THE RIGHT TO: