By Luke Sumpter


Cannabichromene (CBC) is one of the lesser-known cannabinoids. At least at the moment. Very little research has been conducted on this compound, although it is believed to be non-psychoactive.

First discovered in 1966, CBC is structurally similar to other cannabinoids. However, it is also believed to play a key role in cannabis’ anti-inflammatory and analgesic properties.

HOW DOES IT WORK?

CBC directly interacts with CB1 and CB2 receptors throughout the body and brain. However, it also works with other receptors, specifically TRPA1 and TRPV1[1]. These channels, like the endocannabinoid system (ECS) comprised of cannabinoid receptors, link throughout the body. They play a key role in pain and inflammation transmission signals sent to other regions of the body.

Why? “TRP” stands for “transient receptor potential channels” This means that they are essentially the SOS channel over which signals about pain and inflammation are sent.

Even more interesting? CBC is one of the most prevalent, if still largely unresearched cannabinoids. It is also the third most abundant cannabinoid found in generalised plant samples, behind THC and CBD.

Body, Cannabinoids and Receptors

A MULTICHANNEL KEY?

What this means for how cannabinoids will be combined is huge. Perhaps these “extra,” non-psychoactive cannabinoids like CBC act like additional keys or codes. The ECS may in fact be the master regulator. However, side “channels” as it were - such as other switching networks in the body, may also be stimulated by the additional cannabinoids in the cannabis plant.

Confused? Think about the human body like an electrical system or a series of canals. The ECS appears to be one "channel" with cannabinoid receptors. Yet, cannabis also appears to have the ability to send signals into other "channels" too. It may well be that cannabinoids stimulate the ECS the most, but they can also access different receptors as well.

If that is true, then CBC in particular may become a “specialty” cannabinoid all its own. Indeed, it may eventually even be employed to treat or benefit a specific class of health conditions. This in and of itself is a revolutionary way to think not only about CBC, but an entire network of other potentially beneficial cannabinoids as well.

CBCA AND ITS POTENTIAL

Cannabichromenic acid, or CBCA, is the parent molecule of CBC and is one of the three primary cannabinoids formed from cannabigerolic acid (CBGA). CBGA is one of the first cannabinoid produced by cannabis plants and, over time, is broken down by specific enzymes to form THCA, CBDA, and CBCA. Eventually, when cannabis is exposed to heat and UV light during the drying, curing, and smoking/vaping/cooking processes, CBCA is broken down further into CBC and CBL, and CBLA.

To date, little research has looked specifically at the effects of CBCA on the body and it was believed that it does not have therapeutic properties of its own. Nowadays, scientists think it is possible that CBCA exerts anti-inflammatory, antimicrobial and analgesic effects.

WHAT CONDITIONS DOES CBC TREAT?

Apart from generalities of “inflammation” or “pain,” CBC is already starting to be applied to other conditions. New research published last year by the Journal for Experimental Dermatology found that CBC may be good for acne treatment. Why? it appears to reduce the production of sebum by sebaceous glands, while also reducing the impact of arachidonic acid on the skin and glands.

It is not known, thanks to lack of research and data, how exactly CBC can manage pain. However, it is clear that it can and most likely will be used to do so in future trials and treatments. This begins with any movement disorder where inflammation is also a feature, such as arthritis.

Even more thrilling? CBC appears to promote neurogenesis, the growth of nervous tissue. It also may be a key cannabinoid that impacts or retards cell degeneration in conditions like depression, Alzheimer’s, Parkinson’s, Huntington’s, and motor neuron disease.

The properties of this cannabinoid are no doubt intriguing. Even with few human trials to back it up, CBC is already making waves.

cannabichromene

1. CBC and neurogenesis. A mouse study[2] published in 2013 suggests that CBC can positively encourage new cell growth.

2. CBC may be good for reducing chronic stress and depression. A University of Mississippi study found rat subjects[3] treated with CBC to perform better on stress tests.

3. CBC is an anti-inflammatory.[4] A 2010 study found CBC to initiate anti-inflammatory benefits all on its own. However, it also appears to work better when combined with THC and CBD. The combination of all three was more effective than the combination of just the other two.

4. This little cannabinoid might have a huge impact on pain. A 2011 study[5] found that CBC stimulated pain-relieving networks in animal models.

5. CBC has clear anti-bacterial properties, which have been identified for at least thirty years. Studies in the 1980’s even indicate that CBC might be directly impactful against deadly bacterial killers like E. coli[6].

WHAT STRAINS OF CANNABIS ARE HIGH IN CBC?

Research dating back to the 1970’s shows that landrace strains from India carry a high level of CBC. In fact, in these samples, CBC appears to be more abundant than CBD. CBC is also found in higher levels in younger plants. It degrades naturally to another cannabinoid called cannabicyclol in the presence of heat and light. These days, however, most crops are optimised for THC and CBD content. In fact, a 2013 study analised the cannabinoids of one of Europe’s most widely distributed medical strains called Bediol. Both CBC and CBN - another “minor” cannabinoid, were both identified as trace elements.

External Resources:
  1. The functions of TRPA1 and TRPV1: moving away from sensory nerves https://www.ncbi.nlm.nih.gov
  2. The effect of cannabichromene on adult neural stem/progenitor cells - ScienceDirect http://www.sciencedirect.com
  3. Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. - ScienceDirect http://www.sciencedirect.com
  4. Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol. - PubMed - NCBI https://www.ncbi.nlm.nih.gov
  5. Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action. - PubMed - NCBI https://www.ncbi.nlm.nih.gov
  6. Biological activity of cannabichromene, its homologs and isomers. - PubMed - NCBI https://www.ncbi.nlm.nih.gov
Disclaimer:
This content is for educational purposes only. The information provided is derived from research gathered from external sources.

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Privacy Policy - Royal Queen Seeds

To ensure a safe online environment and guarantee adequate data protection, we strictly comply with all legal requirements. In this privacy statement, we provide information about how and for what purpose data is collected, safety measures, storage periods and contact details.


COMPANY NAME: SNORKEL SPAIN, SL (hereinafter ROYAL QUEEN SEEDS)

C/ Vilar d'Abdelà, 5 (nave 1) CP: 08170 de Montornès del Vallès

+34 937 379 846

support@royalqueenseeds.com


The present Privacy Policy sets out the terms on which we will treat personal data at ROYAL QUEEN SEEDS; this includes any personal data collected through our website https://www.royalqueenseeds.com/ as well as any other data we process in the course of our business activities.

ROYAL QUEEN SEEDS collects the following personal data for the purposes listed below:

SECTION 1 – PERSONAL INFORMATION WE COLLECT

1.1 Account purchases

Account purchases can only be made if you are in possession of a personal account. When you create an account or purchase something from our shop, as part of the buying and selling process we collect the following personal information that you provide to us:

This information is required for delivery. In addition, when you browse our shop, we automatically receive the Internet Protocol (IP) address of your computer. Based on this information, we can optimise your online experience and at the same time protect our online environment.

Purpose of data collection

We collect and store account-related data for the following purposes:

(a) to carry out obligations arising from any contracts between you and us, and to provide you with information, products and services that you may request from us;

(b) to set up, manage and communicate with you about your account and your orders;

(c) to conduct market research and analysis;

(d) to confirm your age and identity, and to detect and prevent fraud.

1.2 Newsletters

With your explicit permission, we may send you newsletters about our shop, new products and other updates. We send newsletters based on your explicit consent. In the event that you purchase a product, and in accordance with current regulations, we may send you commercial communications in accordance with the legitimate interest of our company, always about products or services similar to those you have purchased or contracted. In any case, you may exercise your right of opposition through the channels announced in this Privacy Policy. The following information is collected in relation to the newsletter:

We do not need to know the sex of the person in order to send the newsletter (data minimisation: by law we must ask for data that is strictly necessary to provide the service, and in this case knowing the sex is not necessary to send the newsletter).

Purpose of data collection

The data collected is used to:

(a) personalise our emails, including your name and gender;

(b) provide gender-specific content.

You can withdraw your consent at any time by using the link provided in the newsletter or the contact information provided in section 2.

1.3 Customer service and contact form

In order to provide appropriate support, our customer service employees have access to information related to the account. Consequently, their support will be highly effective and friendly. The data provided in our contact form is used by our CRM provider, SuperOffice. We will only use your details to respond to your message.

SECTION 2 – LEGITIMATE INTEREST

If you have purchased any of our products, please note that we may process your personal data for promotional purposes, based on Royal Queen Seeds' legitimate interest only to offer you products or services from our company and about products or services similar to those you have purchased. You may exercise your right to opt out of future messages by the means set out in this Privacy Policy or through any notification you receive.

2.1 How do you withdraw consent?

If you change your mind, you can withdraw your consent for us to contact you for the purpose of collecting, using, or disclosing your data at any time by reaching out to us at: support@royalqueenseeds.com.

SECTION 3 – DISCLOSURE

We may disclose your personal information if we are required to do so by law or if you breach our Terms of Service.

SECTION 4 – HOW LONG DO WE KEEP YOUR DATA?

At Royal Queen Seeds, we will not retain your data for longer than is necessary for the purposes described in this Policy. Different retention periods apply for different types of data; however, the longest period we will normally hold any personal data is 10 years.

4.1 Account information

Data relating to the account remains relevant for as long as the consumer is in possession of an account. Therefore, the data remains documented for as long as the account exists. When our customers delete an account, the associated data will be deleted within a reasonable period of time. Requests regarding the inspection or correction of stored personal data or the deletion of an account can be sent to support@royalqueenseeds.com.

4.2 Newsletters

In the event that you give us your consent to inform you about our products or services, we will keep your data until you express your wish not to receive any further communications from us. However, we regularly (every month) carry out a relevance check. Registered customers (and their personal information) will be deleted whenever customers do not reply to our request. In addition, our newsletter mailing has an opt-out feature. Consumers can withdraw their consent by using this opt-out feature.

SECTION 5 – COOKIES

Cookies are small information files that notify your computer of previous interactions with our website. These cookies are stored on your hard drive, not on our website. Essentially, when you use our website, your computer displays its cookies to us, informing our site that you have visited before. This allows our website to function more quickly and remember aspects related to your previous visits (such as your username), making your experience more convenient. At Royal Queen Seeds, we use two types of cookies: functional and analytical.

5.1 Functional Cookies

Functional cookies are used to enhance your online experience. Among other things, these cookies track what is added to your shopping cart. The use of these cookies does not require prior authorization.

5.2 Analytical Cookies

Analytical cookies are used for research and market analysis. The data collected with these analytical cookies is anonymous, making it unusable for third parties. The use of these cookies does not require prior authorization.

SECTION 5 – THIRD-PARTY SERVICES

Third-party services are required to conduct transactions and provide our services. In general, the third-party providers we use will only collect, use and disclose your information to the extent necessary to enable them to perform the services they provide to us.

However, certain third-party service providers, such as payment gateways and other payment transaction processors, have their own privacy policies regarding the information we must provide to them for your transactions.

We encourage you to read the privacy policies of these providers so that you can understand how these providers will handle your personal information.

In particular, certain suppliers may be located or have facilities located in a different jurisdiction than yours or ours. Therefore, if you choose to proceed with a transaction involving the services of a third party, your information may be subject to the laws of the jurisdiction in which that service provider or its facilities are located.

Once you leave our website or are redirected to a third-party website or application, you are no longer governed by this Privacy Policy or the Terms of Service of our website.

Web analytics service (anonymous data)

On this website we have integrated an element of a web analytics service (with anonymisation functionality). Web analytics can be defined as the gathering, processing and analysis of data about the behaviour of visitors to websites. An analytics service collects, among other things, data about which website a person came from (the so-called referrer), which sub-pages they visited or how often and for how long they visited a sub-page. Web analytics is mainly used for website optimisation and for a cost–benefit analysis of internet advertising.

Courier service

To complete deliveries we use a courier service. This courier service carries out the delivery between our company and the consumer's home. To complete these logistics, the company requires access to the consumer's name and address information.

Mailing service

Royal Queen Seeds uses a third-party mail service provider to send its newsletter. This provider has access to limited account information related to opt-in consent (e.g. email address).

Marketing services

Royal Queen Seeds has the support of a company that specialises in marketing and communication activities. Their access to personal information is very limited and mostly anonymous.

Payment services

At Royal Queen Seeds we use external payment services to handle our transactions (e.g. credit card payments).

SECTION 6 – SECURITY

To protect your personal information, we take reasonable precautions and follow industry standard best practices to ensure that it is not inappropriately lost, misused, accessed, disclosed, altered or destroyed.

If you provide us with your credit card information, the information is encrypted using secure socket layer technology (SSL) and stored using AES-256 encryption. Although no method of transmission over the internet or electronic storage is 100% secure, we follow all PCI-DSS requirements and implement additional industry standards that are commonly accepted. Information related to the account is protected with a hashing method. This method transforms the information into a generated hash. As a result, confidential information is protected and invisible, even to us. In addition, our databases are exceptionally protected against unauthorised access. For example, access to the database is only possible and permitted via approved IP addresses (e.g. from Royal Queen Seeds headquarters). Other attempts and addresses are rejected at all times.

Furthermore, data is anonymised as much as possible, so it cannot be directly linked to a specific consumer. With this data, however, we may be able to carry out market research and analysis. In addition, the third parties concerned (e.g. mailing service) are examined prior to our collaboration, comply with the GDPR from the EU and receive a processing agreement. Within Royal Queen Seeds, employees are assigned different access permissions. Specific permission provides access only to information that is strictly required to perform a task. Digital security measures are subject to change and must meet high requirements to ensure the safety of online customers. That is why, at Royal Queen Seeds, we appoint a security officer. Regular verification and improvement of security measures (where necessary) are part of the role.

SECTION 7 – CHANGES TO THIS PRIVACY POLICY

We reserve the right to modify this Privacy Policy at any time, so please check back regularly. Changes and clarifications will be effective immediately upon being published on the Website. If we make substantial changes to this policy, we will notify you here that it has been updated so you will know what information we collect, how we use it and under what circumstances, if any, we use and/or disclose it.

SECTION 8 – YOU HAVE THE RIGHT TO: