Top 5 Giggly Strains of 2025

Everybody smokes cannabis for different reasons. Some people cherish the relaxing effects, whereas others love to delve deep into conversation. Then there are those smokers that love cannabis simply because it helps them to loosen up and laugh!

Cannabis allows us to take things, and ourselves, less seriously. The herb helps us to see life through a humorous lens, and makes even the most mundane things seem utterly hilarious.

But why does cannabis make people laugh so much? And not just the typical chuckle, but intense giggles and laughter that comes from the belly?

Why Humans Laugh

First things first, why do humans laugh at all? It turns out laughter plays an important part in human interaction. So much so that we all started laughing before we uttered our first words.

Laughing serves as an important social cue. It allows us to signal to others that we’re keen on connecting with them. From an evolutionary point of view, laughter probably alerted strangers—unsure of each other's motives—that they were in safe company.

Among friends and family, laughter may even serve as a replacement for primate grooming. We don’t have full-body fur coats anymore, but laughter works as a perfect replacement for forming and maintaining close bonds.

If passing a joint around a circle of your friends wasn’t enough to make you feel close, the laughter that erupts by the time it burns down certainly will!

Why Laughing Is Good for You

You’ve heard the quote “laughter is the best medicine” many times in your life, and there’s a reason this saying gets espoused so often. A good giggle releases a flurry of happy brain chemicals, and generally does the body a whole lot of good. Check out the main benefits of regular laughter below:

Why Does Cannabis Make You Laugh?

We all know that cannabis catalyses laughter. You’ve probably got more memories than you can count where you and your friends burst into hysterics. But why exactly does the herb make you laugh?

As with almost every aspect of cannabis science, we’re still in the process of figuring this all out. However, some good progress shows that smoking weed makes everything more humorous by shifting cognitive activity^[1].

More specifically, once THC enters the brain, it starts revving up certain groups of neurons associated with laughter. Cells within the frontal and temporal lobes receive more oxygen and nutrients as blood flow within these areas increases.

Smoking weed also plunges users into a relaxed and blissful state of mind. It elevates the mood way past baseline, to the degree that we find ourselves slumped into the couch, talking about all manner of trippy topics with goofy smiles across our faces.

We’re much more likely to start giggling at silly statements and terrible jokes when we’re relaxed. Seeing as modern humans are usually locked in a state of stimulation and stress, these effects become much more amplified when we finally get some downtime.

Which Strain Type Makes You Laugh More — Indica or Sativa?

Traditionally, the terms “indica” and “sativa” describe two subspecies of cannabis that offer different psychotropic effects. Indica strains have long been associated with stoning the body and producing a relaxed mental state. In contrast, sativa varieties are those that typically energise the mind and body.

However, the idea of indica and sativa effects has become outdated. Cannabis scientists have discovered that it’s most likely the terpenes—aromatic molecules responsible for the unique smell and taste of each strain—that underpin these differences in effect. Both indica and sativa strains can possess wildly different terpene profiles, and don’t necessarily autumn into their traditional effects categories.

Some research has even suggested scrapping the word “strain” altogether, as plants of the same strain can even produce different terpene profiles depending on environmental conditions. Instead, they suggest using the term “chemovar” (chemical variety) to classify cannabis.

Chemovars higher in certain terpenes are more likely to make you laugh at classic stoner flicks than others. For example, the relaxing terpene myrcene helps smokers to lower their defences and chill out, increasing the likelihood of achieving a belly laugh or two.

What terpenes make you laugh?

Limonene and pinene also work wonders by enhancing mood and helping smokers feel at ease. These terpenes will have you zoning in on the conversation, catching every sentence uttered, and ultimately giggling and smiling more.

The Best Cannabis Strains To Induce the Giggles in 2025

Pretty much every cannabis strain has the potential to make you burst into laughter. However, some do a much better job than others at putting the mind in that special giggly place. The cultivars below will get you deeply relaxed and have you booming with laughter in no time. These are the giggliest cannabis strains of 2025.

Wedding Cake

There's a reason Wedding Cake is the name on every smoker's lips—this sugary-sweet and potent hybrid boasts unbeatable effects and all-star genetics.

A descendant of Girl Scout Cookies and Cherry Pie, Wedding Cake is infused with loads of THC and mouth-watering terpenes. Immediately upon putting a flame to her flowers, Wedding Cake will fill the room with a sweet biscuit aroma with complex hints of earth, herbs, and vanilla. Meanwhile, with 24% THC (sometimes more), one or two tokes is all it takes for Wedding Cake to lull you into a happy, silly stone. Her effects quickly uplift the mind while completely numbing the body, making her an ideal strain for watching movies or lounging around at home on the weekend. Plus, her 8–10-week flowering phase and solid yields (500g/m² indoors and 600g/plant outdoors) are sure to delight you at harvest time.

Wedding Cake

Wedding Cake

	Girl Scout Cookies x Cherry Pie
	450 - 500 gr/m2
	70 - 120 cm
	8 - 10 weeks
	THC: 20%

	Sativa 20% Indica 80%
	550 - 600 gr/plant
	120 - 150 cm
	Early October
	Laughter, Physically Relaxing, Uplifting

Buy Wedding Cake

Pink Runtz

With a titanic THC content of 26% and a long-lasting and uplifting high, Pink Runtz easily ranks as one of the best giggly strains you can get your green fingers on.

Our breeders created this powerhouse by crossing parent varieties Gelato, The Original Z, and Pink Panties, giving rise to a progeny with 50% indica genetics and 50% sativa. Sow your seeds into cell trays and turn your light on for 24 hours a day as sprouts emerge to prevent legginess and speed up growth. Watch your seedlings grow to 3 cm by the end of week one. Once transplanted into larger fabric pots, you'll watch your specimens reach 6 cm by the end of week two, 15 cm during week three, and 25 cm during week four. Apply LST during this time if you want to keep plants as compact as possible, and move any specimens into a sunny spot if you plan to finish them off outdoors. Transition indoor plants to bloom during week seven of veg by reducing the light cycle to 12 hours on and 12 hours off.

As they stretch during early bloom, your Pink Runtz plants will grow to 100–180 cm, depending on the pot size you’ve selected and the training techniques you’ve implemented. Flush your plants during the final two weeks before harvest, and prepare to bring in up to 475 g/m² from indoor plants after a flowering phase of 8–9 weeks. Outdoors, you’ll pull in 425–475 g/plant during the middle of October. Brace yourself for an outrageously giggly high and delightful flavours of candy, fruit, and pineapple.

Pink Runtz

Pink Runtz

	Gelato x The Original Z x Pink Panties
	425 - 475 gr/m2
	100 - 150 cm
	8 - 9 weeks
	THC: 26%

	Sativa 50% Indica 50%
	450 - 500 gr/plant
	140 - 180 cm
	Middle of October
	Laughter, Long Lasting , Uplifting

Buy Pink Runtz

Royal AK Automatic

Despite her weaponised name, Royal AK Automatic spreads nothing but peace and love.

In fact, this giggly cannabis strain will have you laughing with complete strangers at parties and gatherings. She’ll put your mind at ease within minutes of taking your first toke, and things only go upwards from there.

Her moderate THC level of 15% hits the sweet spot between clear-headed and way too high. You’ll feel social, talkative, and witty. Plus, her earthy, peppery, and sour terpenes light up the taste buds with every hit. Just because you might end up buckling with laughter doesn’t mean you won’t get anything done. As well as being prompted to look on the bright side, you’ll experience waves of motivation. Blaze these buds throughout the day for positive vibes and productivity.

Royal AK Automatic boasts a rapid flowering time of 6–8 weeks, with a total life cycle of 11–12 weeks. Expect great yields wherever you grow her. Indoor plants produce up to 350g/m², while outdoor specimens will fill your stash jars with 160g/plant.

Royal AK Auto

Royal AK Auto

	AK 47 x Ruderalis
	275 - 350 gr/m2
	60 - 70 cm
	6 - 8 weeks
	THC: 15%

	Sativa 35% Indica 40% Ruderalis 25%
	110 - 160 gr/plant
	70 - 100 cm
	11 - 12 weeks after sprouting
	Laughter, Motivating

Buy Royal AK Auto

Hyperion F1

As one of the top giggly strains of cannabis out there, Hyperion F1 combines high concentrations of THC and a complex terpene profile to induce a laughter-filled experience.

Our breeders created this phenom during a long process that involved creating and crossing highly pure inbred lines from parent strains Amnesia, Lemon, and Sin Tra Bajo Automatic. Sow seeds directly into 11 l fabric pots and expect your seedlings to reach a height of 3–4 cm by the end of the first week of growth. During weeks two and three, plants will grow to 13 cm and 35 cm, respectively. Apply LST during this time and move any plants outdoors if you intend to finish them under the sun. Defoliate lightly during week four as your plants start to develop preflowers and transition into bloom.

During bloom, your Hyperion F1 specimens will stretch to a max height of 60–90 cm. Flush your plants during the last two weeks of the 50–55-day flowering phase to improve the smoothness and flavour of your buds. Make sure you have enough stash jars to handle XXL yields from both indoor and outdoor plants. After drying and curing your buds, you’ll experience a euphoric and giggly effect fuelled by high levels of THC and large concentrations of the terpenes farnesene, myrcene, ocimene, and terpinolene.

Hyperion F1

Hyperion F1

	Amnesia x Lemon x Sin Tra Bajo Automatic
	50 - 55 days
	THC: Very high
	Laughter, Motivating , Physically Relaxing, Sleepy
	80 - 85 days after sprouting

Buy Hyperion F1

Mimosa

Minosa harnesses high levels of THC and earthy terpenes to tweak the central nervous system in the direction of ab-busting laughter.

Our breeders at Royal Queen Seeds created this sativa-dominant polyhybrid by crossing the sweet and fruity parent strain Clementine with the potent variety Purple Punch. If you’re in the mood for a hearty chat and near-endless laughter, fire up these buds.

Mimosa produces large colas with dark green sugar leaves and plentiful orange pistils. These buds possess a high trichome count that put in their work during late flowering to manufacture a THC content of 22% and boatloads of earthy and sour terpenes.

If you’re low on space, Mimosa will enable you to grow some giggle-inducing buds with no issues. Indoor plants grow as small as 60cm and still offer up to 400g/m² after a flowering time of 9–10 weeks. Outdoors, this cultivar reaches a height of 80–100cm and rewards growers with 500–550g/plant during October.

Mimosa

Mimosa

	Clementine x Purple Punch
	350 - 400 gr/m2
	60 - 80 cm
	9 - 10 weeks
	THC: 22%

	Sativa 70% Indica 30%
	500 - 550 gr/plant
	80 - 100 cm
	Middle of October
	Creative, Laughter

Buy Mimosa

Laughter and Cannabis Is the Best Medicine

Laughter really is the best medicine. When you’re feeling down, isolated, or in your head, a good laugh with friends or family will almost always make you feel better. Use the giggly cannabis strains mentioned above to truly take advantage of the laughter-inducing power of weed.