By Steven Voser

Carpal tunnel syndrome is a painful condition caused by a compressed nerve in the hand. It causes pain, numbness, tingling, and a variety of other symptoms, and affects roughly 3% of the world population. Luckily, thanks to its anti-inflammatory and pain-relieving properties, cannabis may offer an attractive treatment option to patients with carpal tunnel syndrome.


Carpal tunnel syndrome (CTS) is a painful condition affecting the wrist area. More specifically, it is caused by the pinching of the median nerve (one of the largest nerves in the hand). Carpal tunnel syndrome is a recurring condition that tends to get worse over time, meaning it’s important to diagnose and begin treatment as soon as possible.

Continuous pressure on the median nerve can, over time, cause serious nerve damage. This damage is permanent and leads to worse, more intense symptoms.

The carpal tunnel runs through the wrist and serves as a small passageway that protects the median nerve as it passes from the hand to the arm, running all the way up to the neck. The median nerve is one of the main nerves in the hand and controls feeling in the fingers as well as the muscles around the thumb.

Carpal tunnel syndrome occurs when the carpal tunnel compresses the median nerve. This can happen either when the carpal tunnel narrows or when a special tissue surrounding the flexor tendons in the hand swells. This swelling can compress the carpal tunnel and put pressure on the median nerve.



The external pressure that compresses the median nerve causes a wide variety of symptoms. The severity of these symptoms tends to increase over time. When not treated properly, carpal tunnel syndrome can cause permanent damage to the median nerve, which only increases the severity of symptoms.

Some of the main symptoms of carpal tunnel syndrome include:

  • Pain
  • Numbness
  • Tingling
  • Weakness in the hand
  • Shock-like sensations that run through the fingers
  • Pain and shocks running up the arm towards the shoulder


Research suggests that carpal tunnel syndrome is most common in elderly women. There are a number of factors that might increase a person’s risk of developing this condition, including:

  • Genetics: Physical traits like smaller wrists and a more confined carpal tunnel can increase a person's risk of developing CTS. These physical traits may likely be passed on from one generation to another.
  • Hand movement and flexion: Repeated hand movements or engaging in activities that require extreme flexing of the wrists, hands, and fingers may aggravate the tendons in the wrist and cause swelling, which ultimately affects the median nerve.
  • Arthritis: The swelling of the joints in the hand and wrist may affect the carpal tunnel.



Carpal tunnel treatment starts with a medical examination. Your doctor will diagnose you with the condition based on your symptoms as well as a physical examination, which will include tapping, bending, and pressing on various parts of your hand. They will also examine the sensitivity in your hands and, in some cases, use electrophysiological tests as well as imaging like ultrasound, MRIs, and x-rays to better identify the cause of your symptoms.

Once diagnosed, treatment will vary depending on the severity of your symptoms and the stage of your carpal tunnel syndrome. When detected early, the symptoms of CTS can usually be treated with non-surgical methods, including:

  • Bracing and splinting: This keeps the wrist in a neutral position and minimises pressure on the carpal tunnel.
  • NSAID treatment: NSAIDs are safe, well-tolerated drugs that can help relieve the pain and inflammation of this condition.
  • Steroid injections: Corticosteroids are strong anti-inflammatory agents that can help treat carpal tunnel flare-ups.
  • Exercises: Some doctors get their patients to practice specific exercises designed to help alleviate symptoms and relieve pressure around the median nerve.
  • Lifestyle changes: Your doctor will help you identify activities that put extra pressure on your carpal tunnel and exacerbate your symptoms. This may affect your work, exercise regime, or some hobbies that require you to flex or stretch your hand and wrist regularly or for prolonged periods of time.

Carpal tunnel syndrome can also be treated using surgical procedures. These procedures, known as carpal tunnel release, aim to relieve the pressure around the median nerve by increasing the size of the tunnel. The need for surgery will depend on the severity of your symptoms.


Given that the main symptoms of carpal tunnel syndrome are pain and inflammation, cannabis is an attractive option. And while regular medications like NSAIDs and steroids can offer effective relief from carpal tunnel symptoms, their misuse or continued use can cause side effects.

NSAIDs, for example, can cause gastrointestinal bleeding, heartburn, headaches, dizziness, liver and kidney problems, high blood pressure, and much more. Studies show that in the US, around 100,000 people are hospitalised every year from gastrointestinal issues related to NSAIDs alone. It makes looking for alternatives attractive.

Over the last decade, a number studies have shown that various constituents of cannabis have anti-inflammatory and pain-relieving effects. In 2013, for example, researchers from the Tongji University School of Medicine found that CBD[1] may significantly decrease inflammation in an animal-based study of pancreatitis.

In 2012, a study published in the _European Journal of Pharmacology_ suggested that CBD may decrease inflammation[2] in rats with acute lung injury. In 2011, researchers from the University of Naples Federico II found CBD also seemed to reduce chronic inflammation[3] in the gut. Other studies show how CBD could help reduce inflammation caused by arthritis[4] and IBS[5].

This being said, much more research is needed, so it is not yet clear how effectively cannabis can help with carpal tunnel syndrome. Research specifically targeting the condition and its relation to cannabis needs to be conducted. However, current research into the area is promising, if not definite yet.

External Resources:
  1. Anti-inflammatory Role of Cannabidiol and O-1602 in Cerulein-Induced Acute Pancreatitis in Mice - PubMed
  2. Cannabidiol, a Non-Psychotropic Plant-Derived Cannabinoid, Decreases Inflammation in a Murine Model of Acute Lung Injury: Role for the Adenosine A(2A) Receptor - PubMed
  3. Cannabidiol Reduces Intestinal Inflammation Through the Control of Neuroimmune Axis - PubMed
  4. Preliminary Assessment of the Efficacy, Tolerability and Safety of a Cannabis-Based Medicine (Sativex) in the Treatment of Pain Caused by Rheumatoid Arthritis - PubMed
  5. Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview - PubMed
This content is for educational purposes only. The information provided is derived from research gathered from external sources.

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