By Luke Sumpter


Key Points

  • THCV is a novel cannabinoid that produces unique effects.
  • At high doses, it offers an energetic, clear-headed high with a short duration.
  • Researchers continue to test THCV in models of weight management and diabetes.
  • Discover the strains containing the highest THCV levels and try them for yourself.

Although a close cousin of THC, tetrahydrocannabivarin (THCV) offers a distinct experience, exerting a notable psychoactive effect only at higher doses. In small quantities, the cannabinoid produces a clear-headed sensation, and may curb appetite.

Until recently, only certain landrace and wild-type plants served as a viable source of THCV. Now, modern hybrids are being released that offer increased concentrations of this desirable cannabinoid.

THC and CBD still dominate the limelight when it comes to cannabinoids, but THCV is certainly a rising star. Past its recreational uses, researchers are continuing to assess the molecule for its therapeutic potential, especially in the context of weight loss, energy, and mental clarity.

Below, you'll find out everything you need to know about this up-and-coming cannabinoid and the go-to strains to experience it.

Image of a cannabis plant with the chemical formula of THCV on the right. The highlighted text reads

What Is THCV?

So, what exactly is THCV in weed? This molecule belongs to a chemical family found in cannabis (and some other plants) known as cannabinoids. It exists alongside the likes of THC, CBD, and over 100 other similar compounds.

Plants create these chemicals to defend themselves against various external threats, including heat, light, and pests. However, many of them also happen to interact with the human endocannabinoid system (ECS)—a large signalling network found all throughout the body. Much like THC, THCV engages with the CB1 receptors of the ECS.

As their names suggest, THCV and THC have similar molecular structures and, to an extent, effects. However, THCV possesses unique properties that result in different interactions in humans.

These interactions, as it turns out, may have clinical implications. While it’s too early to make any solid conclusions, researchers are currently testing THCV in a range of disease models.

Where Does THCV Come From?

The biosynthesis of THCV follows a similar path as other major cannabinoids, but there are different compounds involved. THCV begins its journey as cannabigerovarin acid (CBGV-A), one of the two precursor “mother” cannabinoids. In contrast, other cannabinoids, including THC, CBD, and CBC, derive from the precursor cannabigerolic acid (CBGA).

Just as enzymes convert CBGA into a number of different cannabinoids, complex proteins also catalyse a different reaction that transforms CBGV-A into THCV-A (tetrahydrocannabivarin acid). THCV-A is then converted to THCV through a process known as decarboxylation—a heat-driven reaction that ejects a carboxyl group from its molecule.

Image showing the chemical structures of three cannabinoids: THC, THCV, and CBD. Each compound is displayed in a separate box with its name at the top.

THCV vs THC: What’s the Difference?

Chemically, the main thing that distinguishes THCV from THC is the presence of a 3-carbon group instead of a 5-carbon group in its molecular structure. As far as effects go, THCV can be just as psychoactive as THC (at high-enough concentrations).

Both THC and THCV interact with the CB1 and CB2 receptors of the endocannabinoid system. At low doses, however, THCV acts as an antagonist of the CB1 receptor, instead of being an agonist like THC.

This means that small amounts of THCV may reduce the psychotropic influence of THC. Low doses may also counteract some of the side effects associated with THC, like anxiety, paranoia, increased heart rate, and even excess appetite. At higher doses, though, THCV becomes an agonist of CB1 receptors (just like THC), thus producing similar psychoactive effects.

THCV’s boiling point is 220°C (428°F), higher than that of THC. This has to be taken into account when vaping high-THCV concentrates, as lower temperatures will fail to target the compound sufficiently.

THC
  • Psychoactivity: Strong, long-lasting effect
  • Effect on appetite: Increases appetite through the “munchies”
  • Mindset & energy: Can induce relaxation and sluggishness
  • Receptor interaction: CB1 partial agonist, CB2 partial agonist
  • Boiling point: Lower (~157°C / 315°F)
THCV
  • Psychoactivity: Shorter effect that’s intense at high doses
  • Effect on appetite: May suppress appetite
  • Mindset & energy: Often promotes clarity and alertness
  • Receptor interaction: CB1 neutral antagonist or partial agonist, CB2 partial agonist
  • Boiling point: Higher (~220°C / 428°F)

THCV Effects: How Does It Make You Feel?

You’re now all clued up on how THCV compares to THC. But what exactly can you expect when you blaze THCV-rich buds or concentrates? Get a better idea of the THCV experience below.

Psychoactive Properties: Does THCV Get You High?

THCV can produce a high, but its effect differs from THC in terms of both intensity and duration. This cannabinoid works in a biphasic manner, meaning its effects change depending on the dose.

At low doses, THCV acts as a neutral antagonist of the CB1 receptor. Simply put, this means the molecule either blocks this site without affecting it, or only partially activates it.

Although small concentrations of THCV don’t induce a high, researchers are exploring sub-threshold doses for their appetite-suppressing and mood-boosting potential.

High doses of THCV, in contrast, do trigger a high. At such concentrations, the cannabinoid becomes a partial agonist of the CB1 receptor, resulting in a psychoactive effect that is somewhat distinct from that of THC. Expect a stimulating, uplifting, and clear-headed effect.

How Long Does THCV’s Effect Last?

Sometimes described as the “race car” cannabinoid, the effects of THCV are reported to come on rapidly and dissipate quickly. While no scientific literature documents the onset and duration of the cannabinoid, limited user reports suggest that THCV offers somewhat of a “short-acting” high that comes on in a burst and wears off in a hurry.

However, THCV likely affects people differently based on several different variables, including dose, consumption method, and individual genetics and metabolism.

Image of a cannabis plant with annotations about the effects of THCV in Polish. The labels describe THCV as psychoactive, long-lasting, stimulating, and uplifting.

THCV Benefits: What the Science Says

The science surrounding cannabinoids still remains early, partly due to the prohibited status of cannabis throughout much of the world. However, scientists are making headway in some areas, including testing various cannabis-derived constituents on models of disease in preliminary studies.

Continue reading to discover the latest findings surrounding the potential benefits of THCV.

Appetite: A Look at the “Diet Weed” Claims

It’s no secret that THC causes the munchies; most smokers can’t resist raiding the fridge during or after a smoking session. THCV, in contrast, could help to curb appetite.

Several preclinical studies[1] suggest that the cannabinoid could act as an appetite suppressant, earning high-THCV strains the nickname of “diet weed”. These investigations looked at the effects of the cannabinoid on food intake and glucose tolerance in animals.

Seeing these early findings, it didn’t take some users long to draw the ambitious conclusion that they could kill two birds with one stone, getting high and losing weight simultaneously.

Caught up in the hype, many weed users drew comparisons between THCV and rimonabant—an anti-obesity drug that blocks the CB1 receptor and is now banned for its serious psychiatric side effects.

THCV does block the CB1 receptor at low doses but doesn’t work in the same way as rimonabant. The research remains far too early to conclude whether THCV impacts weight loss in humans.

However, a metabolic syndrome study[2] that tested THCV/CBD strips on weight loss and blood pressure in human volunteers has helped to advance understanding in this area.

Research[3] has also analysed the effects of THCV on glycemic and lipid parameters in human patients with type 2 diabetes. Future findings in this area could determine if THCV could play a role in addressing this metabolic condition.

Antipsychotic

Researchers have identified a link between using high-THC cannabis strains and psychosis. However, other compounds within the plant are being studied for their potential to help reduce psychotic symptoms—including THCV.

Research published in the British Journal of Pharmacology in 2015 tested THCV on 5-HT1A serotonin receptors in human and rat cells. This study[4] has helped to lay the groundwork for future investigations on the role of THCV in treating mental health conditions.

Energy & Mental Clarity

Aside from its clinical potential, THCV also offers holistic appeal, with benefits to overall well-being and performance. While many strains high in THC often cause sluggishness, strains high in THCV offer an energising, lucid, and cerebral effect that may be appealing to those looking to enhance creativity, motivation, and accomplish certain tasks.

THCV vs CBD: How Do They Compare?

We’ve given you a side-by-side comparison of THCV and THC. But how does THCV compare to CBD? Check out the table below to explore their similarities and differences.

CBD
  • Psychoactivity: Non-psychoactive, no high
  • Effect on appetite: May reduce appetite in some cases
  • Mindset & energy: Can promote relaxation and clear-headedness
  • Receptor interaction: CB1 and CB2 receptor antagonist
  • Boiling point: Lower (160–180°C / 320–356°F)
THCV
  • Psychoactivity: Brief effect that’s intense at high doses
  • Effect on appetite: May suppress appetite
  • Mindset & energy: Often promotes clarity and alertness
  • Receptor interaction: CB1 neutral antagonist or partial agonist, CB2 partial agonist
  • Boiling point: Higher (~220°C / 428°F)

The legal status of THCV is unclear in many countries. Unlike THC, THCV is federally legal in the United States under the 2018 Farm Bill—a piece of legislation that allows the sale of hemp-derived products with THC concentrations under 0.3%.

However, local laws vary between states in the country. While legal in states including Alabama, California, Georgia, and Hawaii, the cannabinoid remains explicitly illegal in Colorado and legally ambiguous or unregulated in other states.

THCV laws also remain confusing across Europe, with regulations concerning cannabinoids varying widely across European states. Given the absence of explicit regulations in many countries, THCV often falls into a gray area.

Drug legislation in most European countries fails to specifically mention THCV, likely because of its novel status. However, the majority continue to prohibit cannabis production and possession, and no EU-approved hemp strains are significant sources of THCV.

Technically, the cannabinoid has become legal by default in countries that have legalized cannabis cultivation, such as Malta and Luxembourg, as citizens can grow high-THCV varieties.

The bottom line: thoroughly research the legal status of THCV in your local area before buying, possessing, or growing cannabis products that contain the cannabinoid.

Will THCV Show Up on a Drug Test?

No drug tests are currently used to specifically detect THCV. However, there are several important factors to keep in mind when using the cannabinoid.

First, all available cannabis strains that possess high levels of THCV also contain enough THC to trigger a positive drug test. Second, even when consuming THC-free concentrates and isolates, you still run the risk of a positive test.

Because THCV shares a similar structure to THC, it produces similar metabolites in the body as it breaks down. THC drug tests are typically triggered by the metabolite THC-COOH, which THCV also produces. If you’re subject to routine drug tests, you should avoid consuming THCV.

Where to Find THCV?

For those curious, there are several different avenues available to experience the effects of THCV, including cannabis flowers from particular strains, edibles such as gummies, and concentrates.

As it stands, most common strains contain less than 1% THCV, which makes this cannabinoid expensive to extract in large quantities. Higher amounts of THCV have been found in descendants of pure sativa landraces from Africa and Nepal.

Breeding hemp strains that are high in THCV and low in THC is one of the new challenges for cannabis breeders, and various other breeders are creating cultivars with notable THCV and THC levels.

If you want to grow weed plants with higher levels of THCV, you can generally look to sativa genetics, but remember that cannabinoid content can vary from harvest to harvest. In turn, note that growing setups that simulate tropical climates are more likely to yield more THCV.

Strains like Durban Poison, Jack the Ripper, and the rare Doug's Varin all possess some of the highest amounts of THCV. African sativas like Power Flower (a progeny of Jack the Ripper like Mother Gorilla) or descendants of Durban Poison (like Royal Cookies) should also develop notable amounts of THCV. However, only Doug’s Varin was specifically bred for THCV.

Discover Royal THCV

Many cannabis users are excited about the rise of “novel” cannabinoids such as THCV. These compounds produce unique effects and are destined to add something new to the cannabis experience.

But, as mentioned, most strains contain only trace levels of THCV. Even the landrace and wild-type varieties that possess the highest concentrations of this molecule only contain up to around 1%. Therefore, it takes a lot of hard work to create varieties with significant levels.

Fortunately for those seeking this cannabinoid, breeders at Royal Queen Seeds pursued this important work with a passion. After crossing a pure African sativa with Durban Haze and stabilising the progeny, they created Royal THCV.

Royal THCV
23_genetic background_1 Pure African Sativa x Durban Haze
33_Yield indoors_1 500 - 550 gr/m2
31_plant height outdoor_1 80 - 120 cm
25_flowering time_1 9 - 10 weeks
29_THC_1 THC: 7%
28_Type Blend_1 Sativa 95% Indica 5%
34_yield outdoor_1 425 - 475 gr/plant
32_plant height outdoors_1 140 - 180 cm
27_harvest period_1 Late October
22_Effect_1 Clear, Motivating , Uplifting
103_cbd icons 05 7%

Buy Royal THCV

This vastly sativa-dominant hybrid produces dense colas that manufacture a THCV content of 7% and equal levels of THC. This fine balance of cannabinoids produces a subtle, inspiring effect that isn’t overwhelming.

Overall, these flowers exert an energising experience, making this strain an excellent choice for daytime use. The addition of THCV counteracts the munchies and helps the mind to remain clear. Welcome tastes of earth, fruit, and herbs accompany the experience.

When it comes to cultivation, Royal THCV makes life easy for growers. She maintains a height of 80–120 cm indoors and produces up to 550 g/m² after 9–10 weeks of flowering. Plants grown outdoors top out at 180 cm and offer a return of 425–475 g/plant in late October.

THCV Gummies & Edibles: What to Expect

Available in dispensaries in certain states in the US, you’ll also find a range of THCV edible products, including gummies. These products vary in both their cannabinoid concentrations and flavors, with options including blueberry, lemon, and strawberry. Many products also contain formulas that include CBD and other cannabinoids.

Much like when ingesting THC, THCV passes through the digestive tract and liver and takes around 30–60 minutes to take effect. However, unlike THC, THCV doesn’t convert into the potent metabolite 11-hydroxy-THC.

Overall, you can expect a shorter and possibly more intense effect with THCV edibles, marked by clear-headedness. However, you should also treat THCV edibles with caution. Start out with low doses and gradually increase the amount you take each session to avoid a negative experience.

Is There a Future for THCV?

THCV certainly has a bright future. While the cannabinoid remains relatively unknown compared to THC and CBD, growing consumer interest indicates that it could become a popular molecule in its own right.

Research remains very early, and confusing and ambiguous laws across the West continue to obstruct the adoption of this compound. However, as research and development continues, and laws move more favorably towards cannabis liberalisation, THCV will likely start cropping up in wellness products and pharmaceutical drug formulations.

Breeding high-THCV strains will also play a critical role in the image of THCV in the mainstream. While challenging due to a lack of genetic stock, we can expect many new cultivars to emerge over the coming years that will give growers more options when it comes to cultivating plants packed with this cannabinoid.

Keep your eyes peeled for the inevitable rise of THCV, and consider growing the strains mentioned above for a taste of what this compound has to offer!

THCV: FAQ

What is THCV, and what is it good for?
THCV is a cannabinoid known for its clear-headed high and fast-acting effects. It’s ideal for users looking to remain sharp and focused.
Does THCV get you high?
Yes. At higher doses, THCV produces a psychoactive effect by binding to the CB1 receptor.
Is THCV legal?
The legal status of THCV remains confusing and blurry across much of the world. While explicitly legal in some American states, it falls into a grey area across most of Europe.
What strains are high in THCV?
Royal THCV and Durban Poison contain notable amounts of THCV.
External Resources:
  1. Tetrahydrocannabivarin is Not Tetrahydrocannabinol - PubMed https://pubmed.ncbi.nlm.nih.gov
  2. Weight Loss and Therapeutic Metabolic Effects of Tetrahydrocannabivarin (THCV)-Infused Mucoadhesive Strips | Cannabis https://publications.sciences.ucf.edu
  3. Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes https://diabetesjournals.org
  4. The phytocannabinoid, Δ⁹-tetrahydrocannabivarin, can act through 5-HT₁A receptors to produce antipsychotic effects - PubMed https://pubmed.ncbi.nlm.nih.gov
Disclaimer:
This content is for educational purposes only. The information provided is derived from research gathered from external sources.

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Privacy Policy - Royal Queen Seeds

To ensure a safe online environment and guarantee adequate data protection, we strictly comply with all legal requirements. In this privacy statement, we provide information about how and for what purpose data is collected, safety measures, storage periods and contact details.


COMPANY NAME: SNORKEL SPAIN, SL (hereinafter ROYAL QUEEN SEEDS)

C/ Vilar d'Abdelà, 5 (nave 1) CP: 08170 de Montornès del Vallès

+34 937 379 846

support@royalqueenseeds.com


The present Privacy Policy sets out the terms on which we will treat personal data at ROYAL QUEEN SEEDS; this includes any personal data collected through our website https://www.royalqueenseeds.com/ as well as any other data we process in the course of our business activities.

ROYAL QUEEN SEEDS collects the following personal data for the purposes listed below:

SECTION 1 – PERSONAL INFORMATION WE COLLECT

1.1 Account purchases

Account purchases can only be made if you are in possession of a personal account. When you create an account or purchase something from our shop, as part of the buying and selling process we collect the following personal information that you provide to us:

This information is required for delivery. In addition, when you browse our shop, we automatically receive the Internet Protocol (IP) address of your computer. Based on this information, we can optimise your online experience and at the same time protect our online environment.

Purpose of data collection

We collect and store account-related data for the following purposes:

(a) to carry out obligations arising from any contracts between you and us, and to provide you with information, products and services that you may request from us;

(b) to set up, manage and communicate with you about your account and your orders;

(c) to conduct market research and analysis;

(d) to confirm your age and identity, and to detect and prevent fraud.

1.2 Newsletters

With your explicit permission, we may send you newsletters about our shop, new products and other updates. We send newsletters based on your explicit consent. In the event that you purchase a product, and in accordance with current regulations, we may send you commercial communications in accordance with the legitimate interest of our company, always about products or services similar to those you have purchased or contracted. In any case, you may exercise your right of opposition through the channels announced in this Privacy Policy. The following information is collected in relation to the newsletter:

We do not need to know the sex of the person in order to send the newsletter (data minimisation: by law we must ask for data that is strictly necessary to provide the service, and in this case knowing the sex is not necessary to send the newsletter).

Purpose of data collection

The data collected is used to:

(a) personalise our emails, including your name and gender;

(b) provide gender-specific content.

You can withdraw your consent at any time by using the link provided in the newsletter or the contact information provided in section 2.

1.3 Customer service and contact form

In order to provide appropriate support, our customer service employees have access to information related to the account. Consequently, their support will be highly effective and friendly. The data provided in our contact form is used by our CRM provider, SuperOffice. We will only use your details to respond to your message.

SECTION 2 – LEGITIMATE INTEREST

If you have purchased any of our products, please note that we may process your personal data for promotional purposes, based on Royal Queen Seeds' legitimate interest only to offer you products or services from our company and about products or services similar to those you have purchased. You may exercise your right to opt out of future messages by the means set out in this Privacy Policy or through any notification you receive.

2.1 How do you withdraw consent?

If you change your mind, you can withdraw your consent for us to contact you for the purpose of collecting, using, or disclosing your data at any time by reaching out to us at: support@royalqueenseeds.com.

SECTION 3 – DISCLOSURE

We may disclose your personal information if we are required to do so by law or if you breach our Terms of Service.

SECTION 4 – HOW LONG DO WE KEEP YOUR DATA?

At Royal Queen Seeds, we will not retain your data for longer than is necessary for the purposes described in this Policy. Different retention periods apply for different types of data; however, the longest period we will normally hold any personal data is 10 years.

4.1 Account information

Data relating to the account remains relevant for as long as the consumer is in possession of an account. Therefore, the data remains documented for as long as the account exists. When our customers delete an account, the associated data will be deleted within a reasonable period of time. Requests regarding the inspection or correction of stored personal data or the deletion of an account can be sent to support@royalqueenseeds.com.

4.2 Newsletters

In the event that you give us your consent to inform you about our products or services, we will keep your data until you express your wish not to receive any further communications from us. However, we regularly (every month) carry out a relevance check. Registered customers (and their personal information) will be deleted whenever customers do not reply to our request. In addition, our newsletter mailing has an opt-out feature. Consumers can withdraw their consent by using this opt-out feature.

SECTION 5 – COOKIES

Cookies are small information files that notify your computer of previous interactions with our website. These cookies are stored on your hard drive, not on our website. Essentially, when you use our website, your computer displays its cookies to us, informing our site that you have visited before. This allows our website to function more quickly and remember aspects related to your previous visits (such as your username), making your experience more convenient. At Royal Queen Seeds, we use two types of cookies: functional and analytical.

5.1 Functional Cookies

Functional cookies are used to enhance your online experience. Among other things, these cookies track what is added to your shopping cart. The use of these cookies does not require prior authorization.

5.2 Analytical Cookies

Analytical cookies are used for research and market analysis. The data collected with these analytical cookies is anonymous, making it unusable for third parties. The use of these cookies does not require prior authorization.

SECTION 5 – THIRD-PARTY SERVICES

Third-party services are required to conduct transactions and provide our services. In general, the third-party providers we use will only collect, use and disclose your information to the extent necessary to enable them to perform the services they provide to us.

However, certain third-party service providers, such as payment gateways and other payment transaction processors, have their own privacy policies regarding the information we must provide to them for your transactions.

We encourage you to read the privacy policies of these providers so that you can understand how these providers will handle your personal information.

In particular, certain suppliers may be located or have facilities located in a different jurisdiction than yours or ours. Therefore, if you choose to proceed with a transaction involving the services of a third party, your information may be subject to the laws of the jurisdiction in which that service provider or its facilities are located.

Once you leave our website or are redirected to a third-party website or application, you are no longer governed by this Privacy Policy or the Terms of Service of our website.

Web analytics service (anonymous data)

On this website we have integrated an element of a web analytics service (with anonymisation functionality). Web analytics can be defined as the gathering, processing and analysis of data about the behaviour of visitors to websites. An analytics service collects, among other things, data about which website a person came from (the so-called referrer), which sub-pages they visited or how often and for how long they visited a sub-page. Web analytics is mainly used for website optimisation and for a cost–benefit analysis of internet advertising.

Courier service

To complete deliveries we use a courier service. This courier service carries out the delivery between our company and the consumer's home. To complete these logistics, the company requires access to the consumer's name and address information.

Mailing service

Royal Queen Seeds uses a third-party mail service provider to send its newsletter. This provider has access to limited account information related to opt-in consent (e.g. email address).

Marketing services

Royal Queen Seeds has the support of a company that specialises in marketing and communication activities. Their access to personal information is very limited and mostly anonymous.

Payment services

At Royal Queen Seeds we use external payment services to handle our transactions (e.g. credit card payments).

SECTION 6 – SECURITY

To protect your personal information, we take reasonable precautions and follow industry standard best practices to ensure that it is not inappropriately lost, misused, accessed, disclosed, altered or destroyed.

If you provide us with your credit card information, the information is encrypted using secure socket layer technology (SSL) and stored using AES-256 encryption. Although no method of transmission over the internet or electronic storage is 100% secure, we follow all PCI-DSS requirements and implement additional industry standards that are commonly accepted. Information related to the account is protected with a hashing method. This method transforms the information into a generated hash. As a result, confidential information is protected and invisible, even to us. In addition, our databases are exceptionally protected against unauthorised access. For example, access to the database is only possible and permitted via approved IP addresses (e.g. from Royal Queen Seeds headquarters). Other attempts and addresses are rejected at all times.

Furthermore, data is anonymised as much as possible, so it cannot be directly linked to a specific consumer. With this data, however, we may be able to carry out market research and analysis. In addition, the third parties concerned (e.g. mailing service) are examined prior to our collaboration, comply with the GDPR from the EU and receive a processing agreement. Within Royal Queen Seeds, employees are assigned different access permissions. Specific permission provides access only to information that is strictly required to perform a task. Digital security measures are subject to change and must meet high requirements to ensure the safety of online customers. That is why, at Royal Queen Seeds, we appoint a security officer. Regular verification and improvement of security measures (where necessary) are part of the role.

SECTION 7 – CHANGES TO THIS PRIVACY POLICY

We reserve the right to modify this Privacy Policy at any time, so please check back regularly. Changes and clarifications will be effective immediately upon being published on the Website. If we make substantial changes to this policy, we will notify you here that it has been updated so you will know what information we collect, how we use it and under what circumstances, if any, we use and/or disclose it.

SECTION 8 – YOU HAVE THE RIGHT TO: